Key Takeaway Laser safety officer (LSO) certification is a way to document that you understand how to run a safe, compliant laser program, from hazard evaluation to protective equipment and emergency procedures. Medical practices, research labs, and cosmetic clinics that use higher-powered lasers often rely on an LSO to oversee safety, training, and incident response. Certification covers ANSI Z136 standards, hazard evaluation, protective equipment, and emergency protocols. I